cees dekker Things To Know Before You Buy
cees dekker Things To Know Before You Buy
Blog Article
‘Of course, that may be about suitable. I search for a Actual physical knowledge of Organic techniques in a bottom-up way. I feel you may distinguish a few strains of analysis in my team in the mean time. The primary fears chromosome construction: How will you receive a metre-lengthy DNA polymer folded and organised in this type of microscopic mobile? Now we have created visualisation approaches that allow for us to study how, by way of example, SMC proteins loop DNA (online video on Youtube) in order to Construct up chromosomes.
But how do morality, the dignity with the human being, my expertise of the this means of daily life, stick to in the motion of atoms? A purely naturalistic viewpoint fails listed here; a Christian perspective, I do think, is a much more fair technique to interpret these elements of truth.’
[Laughs] ‘It was certainly a fantastic threat! At the time, I was well knowledgeable that it could go Completely wrong Which I could turn into a lot less productive, but I just ignored that. Curiosity has constantly been my strongest driving pressure. And fortuitously it all labored out.’
Our perform was speedily adopted up by Some others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 published their findings on transistors produced from single- and multi-walled carbon nanotubes in Applied Physics Letters.
This yielded a breakthrough. Inside of only some months, we have been in a position to evaluate transport through someone single-walled carbon nanotube. Based ceesdekker.net upon reduced-temperature experiments by a superb PhD pupil in my team, Sander Tans (now a valued colleague and professor at Delft University of Know-how with the Lively study lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes were authentic quantum wires with very prolonged (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Our analysis ranges from your biophysics of DNA to synthetic cells and past. Make sure you have a look beneath in the spectrum of our present tasks.
Lots of related developments followed, exactly where our group established various transistor variants including single-electron transistors at space temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled a number of transistors into tiny proof-of-principle electronic circuits.
He also located time to write many guides, deliver Pretty much forty thousand tweets and lead A prosperous analysis team at Delft University of Technological innovation. ‘It doesn’t feel like operate’, he suggests. ‘I’m just terribly curious.’
Understanding fundamental processes regulating the spatial and dynamic organisation of the DNA in live cells.
It absolutely was during this period that Dekker carried out analysis on magnetic spin programs and on sound in superconductors and semiconductors.
An built-in microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
‘That problems the synthetic cell, as Element of the Dutch BaSyC initiative. Craig Venter looked top rated-down in those days and determined about five hundred genes that happen to be minimally needed for your performing cell. We want to glance base-up: how do we transfer from the couple molecules to a complete biological process?
Visualization of unstained DNA nanostructures with Highly developed in-focus transmission electron microscopy methods
2004, discovery of new physics in translocation of DNA as a result of nanopores; initially experimental research of ions conduction in nanofluidic channels; first electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; first biophysics characterization with the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule study of DNA translocation by a restriction-modification enzyme.